L-citrulline is an amino acid that is produced in limited quantities in the liver and intestines. Taken as a dietary supplement, it aids in the processing of ammonia and aids in the metabolism of nitric oxide, which is necessary during physical exertion and beneficial for the proper functioning of the cardiovascular system.
Description and main properties of l-citrulline
L-citrulline is a non-essential amino acid, meaning it can be produced by the human body. It can also be obtained through certain foods, such as watermelon, where it was discovered. Its name comes from “citrullus,” which is Latin for watermelon.
Unlike many other amino acids, L-citrulline is not involved in protein synthesis. However, it plays an important role in the ornithine cycle, helping the body rid itself of some harmful substances, including ammonia.
In addition, L-citrulline has a positive effect on the functioning of the cardiovascular system. In the kidneys, it is converted into another amino acid - L-arginine, which in turn is converted into nitric oxide, which causes vasodilation (widening of blood vessels), relaxing the smooth muscles in the walls of blood vessels. An interesting fact is that taking L-citrulline increases the concentration of arginine in the body more than if you take arginine directly. The reason is the different ways in which the body processes and absorbs the two substances.
Although it is not directly involved in protein production, L-citrulline promotes protein synthesis by stimulating important signaling pathways related to muscle building. Another of its properties is to inhibit the absorption of certain amino acids by the liver, thus limiting its fat accumulation.
Benefits of taking l-citrulline
Increases capacity for physical exertion
By increasing blood flow, L-citrulline increases the amount of oxygen delivered to the muscles. While it is not able to increase its absorption by the whole body, the amino acid helps its use by the working muscles, thus increasing performance and endurance.
Supports cardiovascular health
By participating in nitric oxide metabolism, l-citrulline contributes to the regulation of blood flow. The vasodilation it causes reduces blood pressure in hypertension and prehypertension, which are risk factors for serious cardiovascular diseases.
Helps with erectile dysfunction
The property of l-citrulline to dilate blood vessels and promote oxygen absorption improves symptoms of erectile dysfunction.
Improves cognitive abilities and brain function
Lack of oxygen has a detrimental effect on brain cells. By increasing blood flow, L-citrulline provides the brain with the necessary amounts, thereby supporting its proper functioning and cognition.
Has antidepressant properties
Several studies have linked low levels of arginine and citrulline to an increased risk of depression. One study found a link between bipolar disorder and low levels of nitric oxide. The results of this study suggest that increasing levels of both amino acids may help alleviate symptoms of depression.
The important role that L-citrulline plays in the processes in the human body also determines its ability to help maintain normal body functioning. There is evidence that the amino acid improves the functioning of the immune system and helps with a number of conditions such as sickle cell disease and non-alcoholic fatty liver disease.
Dosage and administration
Application: Contributes to maintaining normal levels of toxins in the body, as well as the normal functioning of the immune and cardiovascular systems.
Note: Not to be used by pregnant or lactating women, or by persons under 18 years of age. Do not take L-Citrulline if you operate heavy machinery. Do not use as a substitute for a varied and nutritious diet. Do not exceed the recommended daily dose.
Recommended daily dose of the product: 2 capsules daily (preferably in the morning, during meals).
Storage: In a cool, dry place, out of reach of children, away from direct sunlight!
Expiration and batch: Marked on the packaging label.
